Hypersensitivity to carbamazepine presenting as pseudolymphoma.
نویسندگان
چکیده
An unusually severe hypersensitivity reaction to carbamazepine is described, in which the patient presented with lymphadenopathy, hepatosplenomegaly, bone marrow suppression, immunosuppression and other features strongly suggestive of a lymphoma.
منابع مشابه
Carbamazepine induced pseudolymphoma syndrome.
syndrome: Recurrent "Cold" staphylococ-cal abscesses. Pseudolymphoma syndrome, as a hypersensitive reaction to anticonvulsant drugs especially phenytoin, carbamaze-pine, tridone and phenobarbitone is well known(l-4). Its pathogenesis is uncertain. It consists of a triad of fever, generalized rash and lymphadenopathy. Varying degrees of VOLUME 34-SEFTEMBER 1997 7. Hill HR, Quie PG. Raised IgE le...
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Anticonvulsant hypersensitivity syndrome (AHS) is an uncommon but potentially fatal adverse effect that can occur from exposure to phenytoin, carbamazepine, or phenobarbital. It has diverse clinical features and a variable presentation which results in a delay in making the diagnosis. The syndrome commonly begins within 3 weeks after initiation of an anticonvulsant. Patients typically present w...
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Hypersensitivity to anticonvulsant drugs have been reported many times. But anticonvulsant hypersensitivity syndrome (AHS) is a potentially fatal drug reaction with cutaneous and systemic reaction to the arene oxide-producing anticonvulsants, phenytoin, carbamazepine, and Phenobarbital sodium. The hall-mark features of this syndrome are: Fever, rash and lymphadenopathy. The epoxide hydrolase en...
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ورودعنوان ژورنال:
- Journal of clinical pathology
دوره 39 11 شماره
صفحات -
تاریخ انتشار 1986